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The Balance of Health

Claim

Vegetarian and vegan diets are associated with lower cholesterol and around a quarter lower relative risk of ischaemic heart disease.

People eating plant-based diets have fewer heart attacks on average. Trials show these diets lower cholesterol, which supports a causal link.

Moderate evidenceHow ratings work

Why this rating: Consistent observational evidence supported by trials on intermediate markers, but no long-term trials of heart attacks themselves, and vegetarians differ in other healthy habits.

Supported by good-quality studies that point the same way, but with gaps: fewer studies, mostly observational data, or some inconsistency.

25% lower relative risk
Lower risk of ischaemic heart disease in vegetarians (relative)Multiple countries, 2017. Source: Dinu et al. (2017).RR 0.75 (95% CI 0.68–0.82) from observational cohorts. Absolute differences are smaller and depend on baseline risk.

Explanation

Large cohort studies find lower rates of heart disease in vegetarians. Randomised trials show that switching to a vegetarian diet lowers LDL cholesterol, a known cause of heart disease.

The relative reduction of about 25% translates into a smaller absolute reduction, because most people's baseline risk over a decade is modest.

Limitations
  • Confounding by lifestyle; few studies isolate vegan diets from vegetarian.
Methodology
  • Meta-analysis of cohort studies for disease outcomes; meta-analysis of randomised trials for cholesterol.

Sources for this claim

Each source links to our record of what it found, its limitations and what we used it for, with a link to the original.

  1. 1
    Vegetarian, vegan diets and multiple health outcomes: a systematic review with meta-analysis of observational studies

    Monica Dinu, Rosanna Abbate, Gian Franco Gensini et al. (2017). Critical Reviews in Food Science and Nutrition.

    Meta AnalysisMeta AnalysisModerate evidenceView original ↗
  2. 2
    Effects of vegetarian diets on blood lipids: a systematic review and meta-analysis of randomized controlled trials

    Fenglei Wang, Jusheng Zheng, Bo Yang et al. (2015). Journal of the American Heart Association.

    Meta AnalysisRandomised Controlled TrialModerate evidenceView original ↗

Cite this record

Vegetarian and vegan diets are associated with lower cholesterol and around a quarter lower relative risk of ischaemic heart disease.. The Balance of Health. https://thebalanceofhealth.com/claims/plant-based-diets-are-linked-to-lower-heart-disease-risk

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